Stats for total mtDNA (group size: 922 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 15.1 - 50.6% 49.4 - 84.9% 1225 - 8009 905 - 3654 3242 - 7902 3861 - 8643 0.2 - 507.0
Median 41.4% 58.6% 4529 2316 4424 5338 20.6
Average ± stdev 41.8 ± 3.8% 58.2 ± 3.8% 4610 ± 540 2393 ± 291 4472 ± 430 5288 ± 436 25.1 ± 24.9
Coefficient of variation 0.09 0.06 0.12 0.12 0.10 0.08 0.99
Pearson correlation
coefficient with log10MLS
0.04 -0.04 0.14 -0.18 -0.23 0.14 -
Pearson p-value
(two tailed)
1.81E-01 1.79E-01 2.16E-05 3.80E-08 4.56E-12 2.20E-05 -
Stats for total protein-coding genes (group size: 919 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 16.7 - 51.9% 48.1 - 83.3% 950 - 5108 692 - 2412 2325 - 4973 2378 - 4862 0.2 - 507.0
Median 41.8% 58.2% 3270 1411 3102 3507 20.6
Average ± stdev 42.2 ± 4.0% 57.8 ± 4.0% 3324 ± 387 1475 ± 199 3102 ± 314 3461 ± 285 25.1 ± 24.9
Coefficient of variation 0.09 0.07 0.12 0.13 0.10 0.08 0.99
Pearson correlation
coefficient with log10MLS
0.06 -0.06 0.16 -0.20 -0.24 0.19 -
Pearson p-value
(two tailed)
9.15E-02 9.24E-02 6.66E-07 1.84E-09 6.17E-14 4.37E-09 -
Stats for D-loop (group size: 573 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 17.6 - 50.6% 49.4 - 82.4% 52 - 1064 29 - 616 91 - 1374 69 - 1436 1.0 - 211.0
Median 38.4% 61.6% 241 147 306 327 21.4
Average ± stdev 38.1 ± 4.9% 61.8 ± 4.9% 270 ± 103 157 ± 53 336 ± 122 356 ± 128 26.1 ± 21.2
Coefficient of variation 0.13 0.08 0.38 0.34 0.37 0.36 0.81
Pearson correlation
coefficient with log10MLS
0.10 -0.10 0.11 0.02 -0.00 0.05 -
Pearson p-value
(two tailed)
1.50E-02 1.54E-02 9.95E-03 5.87E-01 9.99E-01 2.18E-01 -
Stats for total tRNA-coding genes (group size: 922 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 12.9 - 49.5% 50.5 - 87.1% 110 - 3134 85 - 1685 298 - 2782 417 - 3423 0.2 - 507.0
Median 39.5% 60.5% 353 249 404 516 20.6
Average ± stdev 40.0 ± 4.0% 60.0 ± 4.0% 356 ± 100 261 ± 58 408 ± 83 514 ± 101 25.1 ± 24.9
Coefficient of variation 0.10 0.07 0.28 0.23 0.21 0.20 0.99
Pearson correlation
coefficient with log10MLS
-0.10 0.10 0.03 -0.08 0.03 0.10 -
Pearson p-value
(two tailed)
2.70E-03 3.62E-03 3.56E-01 2.20E-02 3.08E-01 2.72E-03 -
Stats for total rRNA-coding genes (group size: 922 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 16.6 - 50.5% 49.5 - 83.4% 140 - 4120 112 - 2303 255 - 5236 376 - 5541 0.2 - 507.0
Median 41.2% 58.8% 598 457 572 902 20.6
Average ± stdev 42.3 ± 4.0% 57.7 ± 4.0% 611 ± 142 479 ± 86 580 ± 163 905 ± 165 25.1 ± 24.9
Coefficient of variation 0.09 0.07 0.23 0.18 0.28 0.18 0.99
Pearson correlation
coefficient with log10MLS
-0.02 0.02 -0.03 -0.14 -0.10 -0.01 -
Pearson p-value
(two tailed)
5.70E-01 5.66E-01 3.54E-01 1.39E-05 3.60E-03 8.02E-01 -
Stats for ATP6 (group size: 919 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 15.3 - 52.3% 47.7 - 84.7% 59 - 272 38 - 160 142 - 324 141 - 260 0.2 - 507.0
Median 41.1% 58.9% 202 76 194 209 20.6
Average ± stdev 41.4 ± 4.2% 58.6 ± 4.2% 205 ± 26 77 ± 12 194 ± 22 205 ± 19 25.1 ± 24.9
Coefficient of variation 0.10 0.07 0.13 0.16 0.11 0.09 0.99
Pearson correlation
coefficient with log10MLS
0.08 -0.08 0.15 -0.13 -0.25 0.19 -
Pearson p-value
(two tailed)
1.21E-02 1.22E-02 5.22E-06 1.15E-04 4.34E-14 7.82E-09 -
Stats for ATP8 (group size: 917 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 10.7 - 50.6% 49.4 - 89.3% 12 - 201 5 - 91 26 - 269 39 - 281 0.3 - 211.0
Median 36.9% 63.1% 53 14 47 65 20.6
Average ± stdev 37.4 ± 6.0% 62.6 ± 6.0% 53 ± 9 14 ± 5 48 ± 11 66 ± 14 24.6 ± 19.2
Coefficient of variation 0.16 0.10 0.18 0.35 0.24 0.21 0.78
Pearson correlation
coefficient with log10MLS
-0.01 0.01 0.17 -0.10 -0.05 0.18 -
Pearson p-value
(two tailed)
8.02E-01 8.02E-01 3.84E-07 1.50E-03 1.59E-01 9.27E-08 -
Stats for COX1 (group size: 919 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 24.1 - 51.3% 48.7 - 75.9% 180 - 534 171 - 349 349 - 670 326 - 543 0.2 - 507.0
Median 43.0% 57.0% 400 258 459 428 20.6
Average ± stdev 43.2 ± 3.4% 56.8 ± 3.4% 407 ± 47 263 ± 19 456 ± 43 424 ± 27 25.1 ± 24.9
Coefficient of variation 0.08 0.06 0.12 0.07 0.10 0.07 0.99
Pearson correlation
coefficient with log10MLS
0.08 -0.08 0.13 -0.09 -0.17 0.14 -
Pearson p-value
(two tailed)
1.94E-02 1.93E-02 1.08E-04 5.99E-03 1.57E-07 1.70E-05 -
Stats for COX2 (group size: 919 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 19.5 - 50.7% 49.3 - 80.5% 61 - 244 55 - 220 138 - 382 168 - 323 0.2 - 507.0
Median 41.4% 58.6% 182 100 184 217 20.6
Average ± stdev 41.5 ± 3.8% 58.5 ± 3.8% 183 ± 21 101 ± 11 184 ± 19 217 ± 17 25.1 ± 24.9
Coefficient of variation 0.09 0.06 0.12 0.11 0.11 0.08 0.99
Pearson correlation
coefficient with log10MLS
0.05 -0.05 0.12 -0.10 -0.20 0.20 -
Pearson p-value
(two tailed)
1.04E-01 1.10E-01 1.51E-04 3.46E-03 5.48E-10 2.01E-09 -
Stats for COX3 (group size: 919 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 17.1 - 52.2% 47.8 - 82.9% 79 - 285 54 - 204 173 - 396 160 - 287 0.2 - 507.0
Median 44.8% 55.2% 229 121 220 215 20.6
Average ± stdev 44.7 ± 3.4% 55.3 ± 3.4% 228 ± 23 122 ± 11 219 ± 22 214 ± 14 25.1 ± 24.9
Coefficient of variation 0.08 0.06 0.10 0.09 0.10 0.07 0.99
Pearson correlation
coefficient with log10MLS
0.08 -0.08 0.18 -0.18 -0.16 0.13 -
Pearson p-value
(two tailed)
1.71E-02 1.74E-02 4.07E-08 9.17E-08 1.40E-06 1.44E-04 -
Stats for CYTB (group size: 917 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 19.4 - 51.8% 48.2 - 80.6% 107 - 670 95 - 264 253 - 505 225 - 541 0.2 - 507.0
Median 43.8% 56.2% 343 150 310 330 20.6
Average ± stdev 43.7 ± 3.5% 56.3 ± 3.5% 345 ± 38 153 ± 18 316 ± 33 327 ± 29 25.2 ± 24.9
Coefficient of variation 0.08 0.06 0.11 0.12 0.11 0.09 0.99
Pearson correlation
coefficient with log10MLS
0.13 -0.13 0.25 -0.22 -0.32 0.19 -
Pearson p-value
(two tailed)
6.01E-05 6.50E-05 4.41E-14 9.65E-12 5.99E-24 5.01E-09 -
Stats for ND1 (group size: 919 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 17.0 - 53.1% 46.9 - 83.0% 92 - 366 50 - 215 207 - 402 170 - 470 0.2 - 507.0
Median 42.8% 57.2% 289 121 265 286 20.6
Average ± stdev 42.9 ± 4.1% 57.1 ± 4.1% 287 ± 32 126 ± 20 269 ± 24 281 ± 29 25.1 ± 24.9
Coefficient of variation 0.10 0.07 0.11 0.16 0.09 0.11 0.99
Pearson correlation
coefficient with log10MLS
0.06 -0.06 0.19 -0.21 -0.33 0.19 -
Pearson p-value
(two tailed)
8.58E-02 8.64E-02 6.76E-09 5.22E-11 4.72E-25 1.15E-08 -
Stats for ND2 (group size: 919 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 13.5 - 54.0% 46.0 - 86.5% 69 - 410 47 - 210 190 - 477 186 - 415 0.2 - 507.0
Median 40.2% 59.8% 319 100 270 352 20.6
Average ± stdev 40.8 ± 5.2% 59.2 ± 5.2% 317 ± 41 107 ± 24 273 ± 32 343 ± 41 25.1 ± 24.9
Coefficient of variation 0.13 0.09 0.13 0.23 0.12 0.12 0.99
Pearson correlation
coefficient with log10MLS
-0.03 0.03 0.10 -0.22 -0.25 0.26 -
Pearson p-value
(two tailed)
3.41E-01 3.42E-01 2.81E-03 5.74E-12 3.69E-14 2.06E-15 -
Stats for ND3 (group size: 919 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 13.6 - 54.4% 38.2 - 86.4% 16 - 132 15 - 82 70 - 188 54 - 137 0.2 - 507.0
Median 42.3% 57.6% 102 44 100 102 20.6
Average ± stdev 42.4 ± 4.6% 57.6 ± 4.7% 102 ± 13 45 ± 7 101 ± 11 98 ± 13 25.1 ± 24.9
Coefficient of variation 0.11 0.08 0.13 0.18 0.12 0.13 0.99
Pearson correlation
coefficient with log10MLS
0.04 -0.04 0.14 -0.16 -0.27 0.20 -
Pearson p-value
(two tailed)
2.49E-01 2.67E-01 3.50E-05 1.60E-06 1.46E-16 1.19E-09 -
Stats for ND4 (group size: 919 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 13.5 - 52.7% 47.3 - 86.5% 115 - 545 60 - 312 285 - 605 281 - 675 0.2 - 507.0
Median 41.3% 58.6% 404 152 380 432 20.6
Average ± stdev 41.7 ± 4.4% 58.3 ± 4.4% 410 ± 51 163 ± 30 379 ± 42 424 ± 38 25.1 ± 24.9
Coefficient of variation 0.10 0.07 0.13 0.19 0.11 0.09 0.99
Pearson correlation
coefficient with log10MLS
0.05 -0.05 0.17 -0.18 -0.20 0.16 -
Pearson p-value
(two tailed)
1.33E-01 1.34E-01 4.56E-07 6.84E-08 1.28E-09 5.07E-07 -
Stats for ND4L (group size: 919 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 14.0 - 56.2% 43.8 - 86.0% 9 - 119 6 - 63 62 - 144 52 - 149 0.2 - 507.0
Median 41.8% 58.2% 87 37 88 84 20.6
Average ± stdev 42.3 ± 5.9% 57.7 ± 5.9% 86 ± 14 38 ± 6 87 ± 10 83 ± 10 25.1 ± 24.9
Coefficient of variation 0.14 0.10 0.16 0.17 0.12 0.13 0.99
Pearson correlation
coefficient with log10MLS
-0.02 0.02 0.04 -0.12 -0.04 0.11 -
Pearson p-value
(two tailed)
4.87E-01 4.85E-01 2.57E-01 1.60E-04 2.75E-01 4.93E-04 -
Stats for ND5 (group size: 918 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 14.4 - 50.6% 49.4 - 85.6% 132 - 692 84 - 368 375 - 738 398 - 807 0.2 - 507.0
Median 41.0% 59.0% 534 205 494 581 20.6
Average ± stdev 41.3 ± 4.1% 58.7 ± 4.1% 538 ± 64 213 ± 33 492 ± 55 576 ± 44 25.1 ± 24.8
Coefficient of variation 0.10 0.07 0.12 0.16 0.11 0.08 0.99
Pearson correlation
coefficient with log10MLS
0.09 -0.09 0.21 -0.20 -0.24 0.16 -
Pearson p-value
(two tailed)
4.60E-03 4.56E-03 1.95E-10 6.77E-10 6.79E-14 1.11E-06 -
Stats for ND6 (group size: 918 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 13.1 - 58.2% 41.8 - 86.9% 29 - 221 15 - 163 42 - 257 78 - 260 0.2 - 507.0
Median 40.3% 59.7% 163 49 91 216 20.6
Average ± stdev 41.7 ± 5.6% 58.3 ± 5.6% 165 ± 22 52 ± 15 90 ± 24 214 ± 17 25.1 ± 24.9
Coefficient of variation 0.13 0.10 0.14 0.30 0.27 0.08 0.99
Pearson correlation
coefficient with log10MLS
-0.02 0.02 0.14 -0.20 -0.05 0.17 -
Pearson p-value
(two tailed)
6.17E-01 6.29E-01 2.25E-05 2.09E-09 1.27E-01 1.99E-07 -
Stats for 12S rRNA gene (group size: 915 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 18.6 - 52.2% 47.8 - 81.4% 15 - 311 13 - 236 23 - 333 18 - 373 0.2 - 507.0
Median 43.4% 56.6% 236 180 208 324 20.5
Average ± stdev 44.3 ± 4.1% 55.7 ± 4.1% 237 ± 27 185 ± 22 207 ± 20 323 ± 29 25.1 ± 24.9
Coefficient of variation 0.09 0.07 0.12 0.12 0.10 0.09 0.99
Pearson correlation
coefficient with log10MLS
-0.01 0.01 0.12 -0.07 -0.07 0.20 -
Pearson p-value
(two tailed)
6.87E-01 6.62E-01 3.16E-04 2.49E-02 3.26E-02 6.82E-10 -
Stats for 16S rRNA gene (group size: 916 species)
GC (%) AT (%) G (bases) C (bases) A (bases) T (bases) Maximum lifespan (yrs)
Range (min-max) 15.4 - 50.1% 49.9 - 84.6% 72 - 4120 66 - 2303 230 - 5236 348 - 5541 0.2 - 507.0
Median 40.2% 59.8% 362 280 365 575 20.6
Average ± stdev 41.1 ± 4.1% 58.9 ± 4.1% 372 ± 135 294 ± 78 372 ± 165 581 ± 168 25.1 ± 24.9
Coefficient of variation 0.10 0.07 0.36 0.27 0.44 0.29 0.99
Pearson correlation
coefficient with log10MLS
-0.02 0.02 -0.06 -0.14 -0.09 -0.05 -
Pearson p-value
(two tailed)
4.65E-01 4.69E-01 8.21E-02 2.63E-05 8.11E-03 1.67E-01 -

Contact: Vadim E. Fraifeld, MD, PhD

Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel

Email:
How to cite us:

If you would like to cite this database please use:
Toren D, Barzilay T, Tacutu R, Lehmann G, Muradian KK, Fraifeld VE. MitoAge: a database for comparative analysis of mitochondrial DNA, with a special focus on animal longevity. Nucleic Acids Res. 2016; 44(D1):D1262-5.